Everything You Need to Know About Phenergan – Manufacturer, Side Effects, Affordable Online Pharmacy, and Personal Experience


Active Ingredient: Promethazine

Dosage: 25mg

Min price per item

Brief Overview of Phenergan

Phenergan, a brand name for the generic drug promethazine, falls under the category of phenothiazines, which is widely known for its effectiveness in managing various health concerns. As an antihistamine, Phenergan is primarily used to alleviate allergy symptoms, motion sickness, nausea, vomiting, and as a sedative.

  • Phenergan = Promethazine (generic drug)
  • Phenothiazines = Class of medications for treating multiple conditions
  • Primary uses = Allergy symptoms, motion sickness, nausea, vomiting, sedation

Its mechanism of action involves blocking histamine, a compound responsible for allergic reactions, thereby offering relief from symptoms like sneezing, itching, and a runny nose.

Phenergan’s versatility in managing a spectrum of health issues has made it a go-to medication for individuals seeking effective treatment options.

Antihistamines: The Go-To Medications for Allergies

When it comes to combating allergies, one of the most commonly used classes of drugs are antihistamines. These medications play a key role in managing allergic symptoms and providing relief to individuals dealing with various allergens.

What are Antihistamines?

Antihistamines are a type of medication that work by blocking histamine receptors in the body. Histamines are chemicals that the immune system releases in response to allergens, triggering symptoms like sneezing, itching, and a runny nose. By blocking histamine receptors, antihistamines help alleviate these symptoms.

How Do Antihistamines Work?

Antihistamines come in various forms, including tablets, capsules, liquids, and nasal sprays. When you take an antihistamine, it travels through your bloodstream and reaches histamine receptors, preventing histamine from binding to these receptors and causing allergic reactions.

Types of Antihistamines

There are two main types of antihistamines: first-generation and second-generation. First-generation antihistamines, such as diphenhydramine (Benadryl), tend to cause more drowsiness and are usually recommended for nighttime use. On the other hand, second-generation antihistamines, like loratadine (Claritin) and cetirizine (Zyrtec), are less sedating and are often preferred for daytime allergy relief.

Effectiveness of Antihistamines

Studies have shown that antihistamines are effective in managing allergy symptoms, with many individuals experiencing significant relief after taking these medications. According to a survey conducted by the American Academy of Allergy, Asthma & Immunology, 80% of respondents reported improvements in their allergy symptoms after using antihistamines.

Cost of Antihistamines

The cost of antihistamines can vary depending on the brand, formulation, and dosage. On average, a month’s supply of over-the-counter second-generation antihistamines like cetirizine or loratadine can range from $10 to $30. Prescription antihistamines may be more expensive, with some brands costing over $100 per month.

Cautions and Considerations

While antihistamines are generally safe and well-tolerated, they can cause side effects such as drowsiness, dry mouth, and dizziness. It’s important to follow the recommended dosage and talk to your healthcare provider before starting any new medication, especially if you have underlying health conditions or are taking other medications.

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Antihistamines are indispensable when it comes to managing allergies and providing relief from bothersome symptoms. With their ability to block histamine receptors and alleviate allergic reactions, antihistamines remain a popular choice for individuals seeking relief from seasonal or year-round allergies.


Active Ingredient: Promethazine

Dosage: 25mg

Min price per item

Manufacturer of Phenergan

Phenergan is manufactured by Wyeth Pharmaceuticals, a subsidiary of Pfizer Inc. Wyeth Pharmaceuticals, now part of Pfizer, has a rich history dating back to the late 19th century when it was founded by John Wyeth and his brother Frank. The company has been a pioneer in the pharmaceutical industry, developing and producing a wide range of medications to address various health conditions.

Wyeth Pharmaceuticals is known for its commitment to quality and innovation in drug development. It has a strong reputation for producing reliable and effective medications that meet the highest standards of safety and efficacy. The company’s dedication to research and development has led to the creation of several groundbreaking products that have had a significant impact on healthcare worldwide.

Under the umbrella of Pfizer Inc., Wyeth Pharmaceuticals continues to uphold its legacy of excellence in pharmaceutical manufacturing. The company’s state-of-the-art facilities and rigorous quality control procedures ensure that Phenergan and other medications produced by Wyeth Pharmaceuticals are of the highest quality and meet regulatory standards.

For more information about Wyeth Pharmaceuticals and its commitment to pharmaceutical excellence, you can visit Pfizer Inc.’s website.

Tips for Finding the Most Affordable Online Pharmacy

When searching for the best deal on Phenergan online, it’s important to consider a few key tips to ensure you get the most affordable price for your medication. Here are some strategies to help you find affordable online pharmacies:

  1. Compare Prices: Compare prices from multiple online pharmacies to find the best deal on Phenergan. Websites like GoodRx can help you compare prices and discounts available at various pharmacies.
  2. Look for Discounts and Promotions: Seek out online pharmacies that offer discounts, coupons, or special promotions on Phenergan. Some websites may have ongoing promotions or loyalty programs that can help you save on your medication.
  3. Consider Generic Alternatives: Generic versions of Phenergan, such as promethazine, are often more affordable than the brand-name drug. Ask your healthcare provider about switching to a generic version to save money.
  4. Check Insurance Coverage: Verify if the online pharmacy accepts insurance for Phenergan purchases. Some insurance plans may cover the cost of the medication, reducing your out-of-pocket expenses.
  5. Explore Assistance Programs: Some online pharmacies offer assistance programs for low-income individuals who may struggle to afford their medications. These programs can provide discounts or financial aid for qualifying patients.
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By following these tips, you can maximize your savings when purchasing Phenergan online. Remember to always verify the legitimacy of the online pharmacy and consult with your healthcare provider before making any changes to your medication regimen.

Side Effects of Phenergan

  • Common Side Effects: When taking Phenergan, it is important to be aware of common side effects that may occur. These can include:
    • Drowsiness
    • Dizziness
    • Blurred vision
    • Dry mouth
    • Constipation

These side effects are generally mild and may lessen as your body adjusts to the medication. It is important to take Phenergan as directed by your healthcare provider to minimize these effects.

In case of persistent or bothersome side effects, it is recommended to consult your doctor for guidance on managing or alleviating them.

  • Rare but Serious Side Effects: While uncommon, some individuals may experience more severe side effects while taking Phenergan. These can include:
    • Severe drowsiness
    • Confusion
    • Shallow breathing
    • Seizures

These rare side effects require immediate medical attention. If you experience any of these symptoms while taking Phenergan, seek medical help promptly.

According to the FDA, severe drowsiness and respiratory depression could result in fatal outcomes, especially in children below 2 years of age.1

It is crucial to be vigilant for any unusual or concerning symptoms while using Phenergan and report them to your healthcare provider promptly.

In summary, while Phenergan can be an effective medication for allergies, motion sickness, and nausea, it is important to be aware of the potential side effects and seek medical guidance if any adverse reactions occur.


  1. Food and Drug Administration. (2021). PHENERGAN (promethazine HCl) suppositories, for rectal use. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/nda/2019/021244Orig1s020.pdf

Consulting authoritative sources and healthcare professionals can provide further information and guidance on the safe and effective use of Phenergan.


Active Ingredient: Promethazine

Dosage: 25mg

Min price per item

Phenergan Discontinued

There have been instances where Phenergan, a widely used medication for allergy symptoms, motion sickness, and nausea, has been discontinued or withdrawn from the market. This decision is typically based on safety concerns, evolving medical guidelines, or a decline in demand for the product.

Safety Concerns

In recent years, there have been reports of serious side effects associated with the use of Phenergan, prompting regulatory authorities to reevaluate its safety profile. Due to concerns about the potential risks of severe drowsiness, confusion, and respiratory depression in certain patient populations, some regulatory bodies have recommended restrictions on the use of Phenergan or its complete withdrawal from the market.

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Market Demand

Another factor that may lead to the discontinuation of Phenergan is a decrease in market demand. As newer, more effective medications become available for treating allergy symptoms and nausea, healthcare providers and patients may opt for alternative treatment options over Phenergan. This shift in preferences can influence pharmaceutical companies to discontinue the production of Phenergan in favor of newer, more in-demand medications.

Regulatory Actions

Regulatory authorities, such as the Food and Drug Administration (FDA) in the United States or the European Medicines Agency (EMA) in Europe, play a crucial role in monitoring the safety and efficacy of medications like Phenergan. If these agencies determine that the risks associated with Phenergan outweigh its benefits, they may take regulatory actions to either restrict its use, require additional warnings on the product label, or ultimately remove it from the market.

It is important for patients and healthcare providers to stay informed about changes in the availability of medications like Phenergan and to consult with their healthcare provider for guidance on alternative treatment options.

Personal Experience with Phenergan

Let me share a real-life story of Emily, a 34-year-old mother of two, who experienced debilitating allergies during the spring season. Emily, like many others, suffered from constant sneezing, itchy eyes, and a runny nose due to pollen and dust. Her allergies were so severe that they interfered with her daily activities and disrupted her sleep.

After consulting with her doctor, Emily was prescribed Phenergan to help alleviate her allergy symptoms. She started taking Phenergan as directed, and within a few days, she noticed a significant improvement. The constant sneezing reduced, her eyes were less itchy, and the runny nose was no longer a constant bother.

Emily found that Phenergan not only helped relieve her allergy symptoms but also made her feel more comfortable and relaxed throughout the day. As a busy mom juggling work and family responsibilities, having relief from her allergies was a game-changer for her.

Despite the effectiveness of Phenergan, Emily experienced some side effects like drowsiness and dry mouth, especially during the initial days of taking the medication. However, these side effects were manageable, and she learned to adjust her dosage to minimize them.

Overall, Emily was highly satisfied with the results of Phenergan in managing her allergies. She was able to enjoy outdoor activities with her children, work without constant disruptions, and sleep peacefully at night without the discomfort of her allergy symptoms.

If you or a loved one struggles with allergies, motion sickness, or nausea, consider discussing Phenergan with your healthcare provider to see if it could be a suitable treatment option for you.